LECLERC Eric

Research Director
CNRS
Biomécanique et Bioingénierie BMBI (UMR 7338)

Expertise

Discover the specialized technical skills and disciplinary affiliations of our members, who represent the federated communities of the Arts & Humanities, Science & Engineering, and Medicine within the Sorbonne University Alliance.

Communities
Health, Medicine & Biology
Skills
Decision making, Mathematical models, Metabolic disorders, Multi omics data integration, Organ on chip, Precision medicine, Problem solving, Stem cells, Tissue Engineering

Activities

Overview the professional milestones, academic responsibilities, and international collaborations that drive our center’s double ambition to excel in both research and education.

Selected publications

- Matsumoto S , Leclerc E, Maekawa T, Kinoshita H, Shinohara M, Komori K, Sakai Y, Fujii T, Integration of an Oxygen Sensor into a polydimethylsiloxane hepatic culture device for two dimensional Gradient Characterization in a PDMS Hepatocyte Culture Device, Sensors and actuators, 273, 1062-1069, 2018

- Jellali R, Zeller P, Gilard F, Legendre A, Fleury M-J, Jacques S, Tcherkez G, Leclerc E, Effects of DDT and permethrin on rat hepatocytes cultivated in microfluidic biochips: metabolomics and gene expression study, Environmental Toxicology and Pharmacology, 59, 1-12, 2018

- Datta S., Gayraud G, Leclerc E., Bois F-Y., Graph_sampler: a simple tool for fully Bayesian analyses of DAG-models, Comput Stat, 1-26, 2017

- Willemin M.E, Desmots S, Le Grand R, Lestremau F , Zeman F, Leclerc E, Moesch C, Brochot B, PBPK modeling of the cis- and trans- permethrin isomers and their major urinary metabolites in rats, Toxicology and Applied Pharmacology, 294:65-77, 2016

- Leclerc E., Hamon J, Bois F-Y, Investigation of ifosfamide and chloroacetaldehyde renal toxicity through integration of in vitro liver-kidney microfluidic data and pharmacokinetic-system biology models, J of Applied Toxicology, 36, 330-339, 2016

International collaborations

University of Tokyo (Japan)