NERI Christian

Research Director

Expertise

Discover the specialized technical skills and disciplinary affiliations of our members, who represent the federated communities of the Arts & Humanities, Science & Engineering, and Medicine within the Sorbonne University Alliance.

Communities
Health, Medicine & Biology
Skills
Computational Biology, Data analysis, Data fusion, Decision making, Knowledge graphs, Machine learning, Multi omics data integration, Networks, Precision medicine, Statistical learning, Stem cells

Activities

Overview the professional milestones, academic responsibilities, and international collaborations that drive our center’s double ambition to excel in both research and education.

Responsibilities

Group leader, Brain-C Lab

Awards

Inserm Avenir, APHP DHU

Selected publications

- https://elifesciences.org/articles/64984

- https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13226

- Bigan E, Nair SS, Lejeune FX, Fragnaud H, Parmentier F, Megret L, Verny M, Aaronson J, Rosinski J, and Néri C. Genetic cooperativity in multi-layer networks implicates cell survival and senescence in the striatum of Huntington's disease mice synchronous to symptoms. Bioinformatics2019, doi: 10.1093/bioinformatics/btz514.2.

- Kacher R, Lamazière A, Heck N, Kappes V, Mounier C, Despres G, Dembitskaya Y, Perrin E, Christaller W, Sasidharan Nair S, Messent V, Cartier N, Vanhoutte P, Venance L, Saudou F, Néri C, Caboche J, Betuing S.CYP46A1 gene therapy deciphers the role of brain cholesterol metabolism in Huntington's disease. Brain 2019142, 2432-2450. doi: 10.1093/brain/awz1743.

- Vergallo, A., Megret, L., Lista, S., Cavedo, E., Zetterberg, H., Blennow, K., Vanmechelen, E., De Vos, A., Habert, M.O., Potier, M.C., Dubois B, Neri C, Hampel H. Plasma amyloid beta 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease. Alzheimers Dement 2019, 15, 764-775.

International collaborations

MIT, UCLA, Buck Institute for Research on Aging, Baylor's College of Medicine

Industrial collaborations

Ariana Pharma, BioMérieux,Biophytis,Bio-Rad, Gene-IT, GSK, Oxyproteomics, Novartis, Roche, Sanofi, Trophos