Eric LECLERC

BMBI
...
  • CNRS Research Director
  • BMBI - Biomécanique et Bioingénierie
  • Communities
    Health, Medicine & Biology
  • Expertise
    Decision making
    Mathematical models
    Metabolic disorders
    Multi omics data integration
    Organ on chip
    Precision medicine
    Problem solving
    Stem cells
    Tissue Engineering

Selected publications

- Matsumoto S , Leclerc E, Maekawa T, Kinoshita H, Shinohara M, Komori K, Sakai Y, Fujii T, Integration of an Oxygen Sensor into a polydimethylsiloxane hepatic culture device for two dimensional Gradient Characterization in a PDMS Hepatocyte Culture Device, Sensors and actuators, 273, 1062-1069, 2018

- Jellali R, Zeller P, Gilard F, Legendre A, Fleury M-J, Jacques S, Tcherkez G, Leclerc E, Effects of DDT and permethrin on rat hepatocytes cultivated in microfluidic biochips: metabolomics and gene expression study, Environmental Toxicology and Pharmacology, 59, 1-12, 2018

- Datta S., Gayraud G, Leclerc E., Bois F-Y., Graph_sampler: a simple tool for fully Bayesian analyses of DAG-models, Comput Stat, 1-26, 2017

- Willemin M.E, Desmots S, Le Grand R, Lestremau F , Zeman F, Leclerc E, Moesch C, Brochot B, PBPK modeling of the cis- and trans- permethrin isomers and their major urinary metabolites in rats, Toxicology and Applied Pharmacology, 294:65-77, 2016

- Leclerc E., Hamon J, Bois F-Y, Investigation of ifosfamide and chloroacetaldehyde renal toxicity through integration of in vitro liver-kidney microfluidic data and pharmacokinetic-system biology models, J of Applied Toxicology, 36, 330-339, 2016

International collaborations

University of Tokyo (Japan)